Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SELL | P14151 | 1/20 | 0.45 |
| ▸ | SELP | P16109 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.45 |
| ▸ | ACLY | P53396 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660848 | 0.88 | CA5A (0.47) | CA5AGAATSHRALDH1A1NFKB1 | |
| SCHEMBL30997420 | 0.88 | CA5A (0.47) | CA5AGAATSHRALDH1A1NFKB1 | |
| SCHEMBL2915192 | 0.87 | GAA (0.47) | CA5AGAATSHRALDH1A1NFKB1 | |
| SCHEMBL8930353 | 0.86 | CA5A (0.67) | CA5AGAATSHRALDH1A1NFKB1 | |
| SCHEMBL8095827 | 0.85 | GAA (0.65) | CA5AGAATSHRALDH1A1NFKB1 | |
| SCHEMBL741235 | 0.81 | ALPL (0.51) | TSHRL3MBTL1NPSR1TRPV4 | |
| SCHEMBL153055 | 0.79 | GAA (0.74) | CA5AGAATSHRALDH1A1NFKB1 | |
| SCHEMBL30049382 | 0.79 | GAA (0.74) | CA5AGAATSHRALDH1A1NFKB1 | |
| SCHEMBL8180786 | 0.78 | TRPV4 (0.46) | CA5AGAATSHRALDH1A1NFKB1 | |
| SCHEMBL921998 | 0.78 | GAA (0.68) | CA5AGAATSHRALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158948-A | Treating neurological and psychological disorders | ABBOTT LABORATORIES (US) | 1992-10-27 | — | — | US | disclosed |