SCHEMBL8096265

SCHEMBL8096265

[c]1cc(-c2ccsc2)nc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 3/20 0.44
PDGFRA P16234 3/20 0.44
CYP2A6 P11509 3/20 0.41
CYP2B6 P20813 2/20 0.41
CYP2E1 P05181 1/20 0.41
NPC1 O15118 1/20 0.41
TOP1 P11387 2/20 0.38
TACR3 P29371 1/20 0.38
GBA1 P04062 1/20 0.36
NQO2 P16083 1/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ADORA2A P29274 2/20 0.35
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
ATR Q13535 1/20 0.34
ADORA1 P30542 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234452 0.80 ACHE (0.47) TOP1NQO2
SCHEMBL4875167 0.80 MAPT (0.46) NPC1NQO2
SCHEMBL8087264 0.79 CYP2C9 (0.53) PDGFRBPDGFRANPC1CYP3A4CYP2C9
SCHEMBL29133411 0.77 DHODH (0.46) NPC1TOP1AR
SCHEMBL4901955 0.75 CYP1A1 (0.41) NPC1ADORA2A
SCHEMBL4912670 0.75 ALDH1A1 (0.45) NPC1NQO2CYP3A4ADORA2A
SCHEMBL4907021 0.75 NPC1 (0.53) NPC1ADORA2A
SCHEMBL5780643 0.75 CYP19A1 (0.47) NPC1TOP1ADORA2A
SCHEMBL30125150 0.74 RAB9A (0.59) PDGFRBPDGFRACYP2A6CYP2B6CYP2E1
SCHEMBL707907 0.74 RAB9A (0.59) PDGFRBPDGFRACYP2A6CYP2B6CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6063956-A APPLYING FUNGICIDE OR INSECTICIDE TO THE LOCUS WHERE CONTROL IS DESIRED ROHM AND HAAS COMPANY (US) 2000-05-16 US disclosed