Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.49 |
| ▸ | JAK1 | P23458 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251488 | 0.86 | KDM4E (0.62) | ADRA1DADRA1AADRA1BL3MBTL1KMT2A | |
| SCHEMBL3478287 | 0.85 | ADRA1D (0.56) | ADRA1DADRA1AADRA1BL3MBTL1KMT2A | |
| SCHEMBL960584 | 0.85 | CTSD (0.51) | ADRA1DADRA1AADRA1BL3MBTL1KMT2A | |
| SCHEMBL6607848 | 0.85 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BKMT2ACXCR2 | |
| SCHEMBL7223357 | 0.85 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BL3MBTL1KMT2A | |
| SCHEMBL31483721 | 0.84 | HTT (0.64) | ADRA1DADRA1AADRA1BL3MBTL1KMT2A | |
| SCHEMBL26417076 | 0.84 | HTT (0.64) | ADRA1DADRA1AADRA1BL3MBTL1KMT2A | |
| SCHEMBL17182409 | 0.84 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BL3MBTL1KMT2A | |
| SCHEMBL23740293 | 0.82 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BL3MBTL1KMT2A | |
| SCHEMBL2001238 | 0.82 | FABP4 (0.48) | ADRA1DADRA1AADRA1BL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |
| US-6030973-A | TYPE II DIABETES (NON-INSULIN-DEPENDENT-DIABETES MELLITUS) POTENTIATION; EFFICIENCY; SIDE EFFECT REDUCTION | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-02-29 | — | — | US | disclosed |