Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096449 | 0.82 | ADRA1D (0.59) | ADRA1DADRA1AADRA1BALDH1A1L3MBTL1 | |
| SCHEMBL13624736 | 0.78 | TSHR (0.41) | ALDH1A1L3MBTL1TP53MAPTHTT | |
| SCHEMBL960584 | 0.76 | CTSD (0.51) | ADRA1DADRA1AADRA1BALDH1A1L3MBTL1 | |
| SCHEMBL6607848 | 0.76 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BALDH1A1JAK2 | |
| SCHEMBL12386087 | 0.75 | MEN1 (0.59) | ALDH1A1L3MBTL1TP53JAK2JAK1 | |
| SCHEMBL14163780 | 0.74 | GAA (0.55) | ALDH1A1LMNAKMT2AMEN1HPGD | |
| SCHEMBL3441356 | 0.74 | AGTR1 (0.54) | ALDH1A1JAK2JAK1KDM4EKMT2A | |
| SCHEMBL2001238 | 0.73 | FABP4 (0.48) | ADRA1DADRA1AADRA1BALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5389527 | 0.73 | AGTR1 (0.53) | ALDH1A1JAK2JAK1KDM4EKMT2A | |
| SCHEMBL3577771 | 0.72 | NPC1 (0.55) | ALDH1A1MAPTLMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3579883-B1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | ADC THERAPEUTICS SA (CH) | 2021-08-11 | — | — | EP | disclosed |