Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 6/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809856 | 0.67 | INMT (0.41) | BACE1BACE2APP | |
| SCHEMBL810119 | 0.66 | INMT (0.41) | BACE1BACE2APPSLC6A2SLC6A4 | |
| SCHEMBL3456304 | 0.65 | BACE1 (1.00) | BACE1BACE2APPCTSD | |
| SCHEMBL10676914 | 0.63 | BACE1 (0.50) | BACE1BACE2APPCTSDSLC6A2 | |
| SCHEMBL14277042 | 0.63 | BACE1 (0.69) | BACE1BACE2APPCTSDPOLB | |
| SCHEMBL10677442 | 0.62 | BACE1 (0.52) | BACE1BACE2APPCTSDSLC6A2 | |
| SCHEMBL14277041 | 0.62 | BACE1 (0.49) | BACE1BACE2APPCTSDPOLB | |
| SCHEMBL991696 | 0.59 | SIGMAR1 (0.46) | BACE1BACE2APPSIGMAR1POLB | |
| SCHEMBL9458539 | 0.57 | OPRM1 (0.35) | SLC6A2SLC6A4SLC6A3GRIN2DGRIN3B | |
| SCHEMBL30929784 | 0.57 | GRIN1 (0.57) | BACE1BACE2APPGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098567-B1 | ACRYLIC RUBBER COMPOSITION AND VULCANIZATE THEREOF | DENKI KAGAKU KOGYO KK (JP) | 2011-11-16 | — | — | EP | disclosed |
| US-8012556-B2 | Acrylic rubber composition and its vulcanized product | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100009105-A1 | ACRYLIC RUBBER COMPOSITION AND VULCANIZED PRODUCT | DENKI KAGAKU KIGYO KABUSHIKI KAISHA (JP) | 2010-01-14 | — | — | US | disclosed |
| EP-2098567-A1 | ACRYLIC RUBBER COMPOSITION AND VULCANIZATE THEREOF | Denki Kagaku Kogyo Kabushiki Kaisha (JP) | 2009-09-09 | — | — | EP | disclosed |