SCHEMBL991696

SCHEMBL991696

c1ccc(N2CCCN3CCCN=C32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.46
TSHR P16473 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.43
CYP2D6 P10635 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C19 P33261 1/20 0.41
SOS1 Q07889 2/20 0.40
APP P05067 1/20 0.40
BACE1 P56817 1/20 0.40
BACE2 Q9Y5Z0 1/20 0.40
CYP1A2 P05177 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HTT P42858 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23075907 0.88 POLB (0.39) TSHRMEN1KMT2APOLBCYP2D6
SCHEMBL13116674 0.87 SIGMAR1 (0.53) SIGMAR1TSHRMEN1KMT2APOLB
SCHEMBL9803211 0.83 SIGMAR1 (0.60) SIGMAR1TSHRMEN1KMT2ANPC1
SCHEMBL23076104 0.83 TSHR (0.41) TSHRMEN1KMT2APOLBCYP2D6
SCHEMBL23075889 0.83 POLB (0.38) TSHRMEN1KMT2APOLBCYP2D6
SCHEMBL23075845 0.82 POLB (0.43) TSHRMEN1KMT2APOLBCYP2D6
SCHEMBL23075775 0.82 MAT2A (0.43) SIGMAR1TSHRMEN1KMT2APOLB
SCHEMBL23075776 0.81 DHFR (0.37) TSHRMEN1KMT2APOLBCYP2D6
SCHEMBL23075905 0.79 HPGD (0.47) TSHRMEN1KMT2APOLBCYP2D6
SCHEMBL23075835 0.79 HPGD (0.47) TSHRMEN1KMT2APOLBCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12173150-B2 Polyester carbonates from cycloaliphatic diacids and aliphatic diols, and process for preparing same COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2024-12-24 US claimed
US-20220073737-A1 POLYESTER CARBONATES FROM CYCLOALIPHATIC DIACIDS AND ALIPHATIC DIOLS, AND PROCESS FOR PREPARING SAME COVESTRO DEUTSCHLAND AG (DE) 2022-03-10 US claimed
EP-3898764-A1 POLYESTER CARBONATES FROM CYCLOALIPHATIC DIACIDS AND ALIPHATIC DIOLS, AND PROCESS FOR PREPARING SAME Covestro Intellectual Property GmbH & Co. KG (DE) 2021-10-27 EP claimed
WO-2020126806-A1 POLYESTER CARBONATES FROM CYCLOALIPHATIC DIACIDS AND ALIPHATIC DIOLS, AND PROCESS FOR PREPARING SAME COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2020-06-25 WO claimed
EP-0543234-A2 Process for the simultaneous preparation of an alkylene glycol and of an alkyle carbonate BAYER AG (DE) 1993-05-26 EP claimed
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio COVESTRO DEUTSCHLAND AG (DE) 2026-01-27 US disclosed
US-12516152-B2 Polyester carbonates having a defined proportion of ester groups COVESTRO DEUTSCHLAND AG (DE) 2026-01-06 US disclosed
WO-2025125431-A1 PRODUCTION OF THERMOPLASTIC POLY(URETHANE-CO-CARBONATE)S BASED ON HIGH-VISCOSITY (HETERO)CYCLOALIPHATIC URETHANEDIOL PREPOLYMERS COVESTRO DEUTSCHLAND AG (DE) 2025-06-19 WO disclosed
WO-2025125432-A1 THERMOPLASTIC POLY(URETHANE-CO-CARBONATE) COVESTRO DEUTSCHLAND AG (DE) 2025-06-19 WO disclosed
EP-4569023-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2025-06-18 EP disclosed
WO-2025068164-A1 SEQUENTIAL PROCESS FOR PRODUCING POLYESTER CARBONATES CONTAINING 1,4:3,6-DIANHYDROHEXITOL COVESTRO DEUTSCHLAND AG (DE) 2025-04-03 WO disclosed
EP-4168468-B1 POLYESTER CARBONATES MADE FROM CYCLOALIPHATIC DIACIDS, 1,4 : 3,6-DIANHYDRO-HEXITOLE AND A FURTHER ALIPHATIC DIHYDROXY COMPOUND COVESTRO DEUTSCHLAND AG (DE) 2025-04-02 EP disclosed
EP-0735073-A2 Process for the preparation of thermoplastic polycarbonate BAYER AG (DE) 1996-10-02 EP disclosed
EP-0726285-A2 Two-step process for the production of thermoplastic polycarbonate BAYER AG (DE) 1996-08-14 EP disclosed
EP-0712878-A2 Process for the preparation of thermoplastic polycarbonate BAYER AG (DE) 1996-05-22 EP disclosed
EP-0709421-A1 Process for the preparation of thermoplastic polycarbonate BAYER AG (DE) 1996-05-01 EP disclosed
EP-0703261-A1 Process for the preparation of thermoplastic polycarbonates BAYER AG (DE) 1996-03-27 EP disclosed
US-5418316-A Guanidine-derived catalyts for preparing polycarbonates by transesterification BAYER AKTIENGESELLSCHAFT (DE) 1995-05-23 US disclosed
EP-0629645-A1 Process for the preparation of thermoplastic polycarbonates BAYER AG (DE) 1994-12-21 EP disclosed
EP-0543234-A2 Process for the simultaneous preparation of an alkylene glycol and of an alkyle carbonate BAYER AG (DE) 1993-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534568-B2 Polyester carbonates consisting of different diols in a defined ratio HSD11B2, HSD11B1, HSD3B1 SIGMAR1 3043/4885TSHR 4701/4885MEN1 461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.