SCHEMBL8096511

SCHEMBL8096511

Cc1cccc(N2CSCC2=O)c1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
MAPT P10636 2/20 0.46
HSP90AA1 P07900 1/20 0.46
MGLL Q99685 1/20 0.46
HSD17B10 Q99714 1/20 0.45
PARP1 P09874 1/20 0.44
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
ALOX5 P09917 1/20 0.43
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
CASP6 P55212 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD11B1 P28845 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8096492 0.81 MAPT (0.64) MAPTMGLLALOX5MEN1GAA
SCHEMBL8099334 0.81 MGLL (0.49) MAPTMGLLALOX5
SCHEMBL8089771 0.80 MAPT (0.46) L3MBTL1MAPTMGLLMEN1GAA
SCHEMBL8099171 0.80 MEN1 (0.51) L3MBTL1MAPTMGLLALOX5MEN1
SCHEMBL8096930 0.80 MEN1 (0.51) L3MBTL1MAPTMGLLALOX5MEN1
SCHEMBL8103929 0.80 ALOX5 (0.45) MAPTALOX5MEN1GAAKMT2A
SCHEMBL8089820 0.79 MAPT (0.47) MAPTMGLLMEN1KMT2A
SCHEMBL8089839 0.78 DRD2 (0.44) MAPTMEN1KMT2AHSD11B1
SCHEMBL6031714 0.78 ALDH1A1 (0.59) MAPTHSD17B10MEN1GAAKMT2A
SCHEMBL8098475 0.76 CTSG (0.47) MAPTMGLLMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672038-B1 HERBICIDES ZENECA LTD (GB) 2000-01-19 EP disclosed
US-5856273-A CONTROLLING WEEDS ZENECA LIMITED (GB) 1999-01-05 US disclosed
EP-0672038-A1 HERBICIDES ZENECA LIMITED (GB) 1995-09-20 EP disclosed
WO-1994013652-A1 HERBICIDES ZENECA LIMITED (GB) 1994-06-23 WO disclosed