Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094545 | 0.82 | POLB (0.36) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL8902496 | 0.82 | MAPK14 (0.39) | HTTMAPTGAAPOLBMEN1 | |
| SCHEMBL9760352 | 0.81 | LMNA (0.46) | HTTMAPTTP53GAAPOLB | |
| SCHEMBL10671062 | 0.81 | PTGS2 (0.44) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL10671168 | 0.79 | TSHR (0.37) | MAPTGAAPOLBMAOBMEN1 | |
| SCHEMBL22721608 | 0.76 | LMNA (0.48) | HTTMAPTTP53GAAMEN1 | |
| SCHEMBL7541194 | 0.75 | HTT (0.33) | HTTMAPTGAAMEN1KMT2A | |
| SCHEMBL20505010 | 0.72 | LIPG (0.46) | CA12CA9 | |
| SCHEMBL10112748 | 0.71 | POLB (0.68) | MAPTTP53GAAPOLBMEN1 | |
| SCHEMBL94221 | 0.71 | POLB (0.42) | HTTMAPTGAAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6118004-A | Cyclobutenedione derivative, manufacturing method thereof and non-linear optical device containing the same | FUJI XEROX CO., LTD. (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0761643-B1 | Cyclobutenedione derivative, manufacturing method thereof and non-linear optical device containing the same | FUJI XEROX CO LTD (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5948915-A | Cyclobutenedione derivative, manufacturing method thereof and non-linear optical device containing the same | FUJI XEROX CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| US-5726317-A | NONLINEAR OPTICAL DEVICE | FUJI XEROX CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0761643-A2 | Cyclobutenedione derivative, manufacturing method thereof and non-linear optical device containing the same | FUJI XEROX CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |