Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CREB1 | P16220 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22721608 | 0.94 | LMNA (0.48) | LMNAMAPTHTTGAAADORA3 | |
| SCHEMBL9554998 | 0.84 | LTA4H (0.49) | LMNAMAPTHTTADORA3LTA4H | |
| SCHEMBL8902496 | 0.81 | MAPK14 (0.39) | LMNAMAPTHTTGAAALDH1A1 | |
| SCHEMBL8094545 | 0.81 | POLB (0.36) | MAPTGAAADORA3KDM4EALDH1A1 | |
| SCHEMBL8096617 | 0.81 | HTT (0.42) | LMNAMAPTHTTGAAKDM4E | |
| SCHEMBL16575411 | 0.81 | PDE4A (0.47) | LMNAMAPTHTTGAAADORA3 | |
| SCHEMBL10671062 | 0.80 | PTGS2 (0.44) | MAPTGAAADORA3KDM4EALDH1A1 | |
| SCHEMBL30846906 | 0.79 | LTA4H (0.43) | LMNAMAPTHTTGAAADORA3 | |
| SCHEMBL10671168 | 0.79 | TSHR (0.37) | MAPTGAAKDM4EALDH1A1RAB9A | |
| SCHEMBL9760097 | 0.78 | PDE4B (0.53) | LMNAMAPTHTTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4986935-A | NONLINEAR OPTICAL DEVICES; COMPOUND HAVING HIGH ACTIVITY FOR SECOND HARMONIC WAVE GENERATION | FUJI XEROX CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4751327-A | Photoconductive imaging members with unsymmetrical squaraine compounds | XEROX CORPORATION (US) | 1988-06-14 | — | — | US | disclosed |
| US-4624904-A | Photoconductive imaging members with unsymmetrical squaraine compounds containing an hydroxyl group | XEROX CORPORATION (US) | 1986-11-25 | — | — | US | disclosed |