Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902496 | 0.82 | MAPK14 (0.39) | POLBGAAMAPTALDH1A1MEN1 | |
| SCHEMBL8096617 | 0.82 | HTT (0.42) | POLBGAAMAPTALDH1A1KDM4E | |
| SCHEMBL9760352 | 0.81 | LMNA (0.46) | POLBGAAMAPTALDH1A1KDM4E | |
| SCHEMBL10671062 | 0.81 | PTGS2 (0.44) | POLBGAAMAPTNQO1ALDH1A1 | |
| SCHEMBL10671168 | 0.79 | TSHR (0.37) | POLBGAAMAPTALDH1A1KDM4E | |
| SCHEMBL22721608 | 0.76 | LMNA (0.48) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL20505010 | 0.72 | LIPG (0.46) | — | |
| SCHEMBL94221 | 0.71 | POLB (0.42) | POLBGAAMAPTNQO1ALDH1A1 | |
| SCHEMBL470104 | 0.69 | NQO1 (0.64) | GAANQO1ALDH1A1KDM4EMEN1 | |
| SCHEMBL9554998 | 0.67 | LTA4H (0.49) | MAPTALDH1A1L3MBTL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6118004-A | Cyclobutenedione derivative, manufacturing method thereof and non-linear optical device containing the same | FUJI XEROX CO., LTD. (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-0761643-B1 | Cyclobutenedione derivative, manufacturing method thereof and non-linear optical device containing the same | FUJI XEROX CO LTD (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5948915-A | Cyclobutenedione derivative, manufacturing method thereof and non-linear optical device containing the same | FUJI XEROX CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| US-5726317-A | NONLINEAR OPTICAL DEVICE | FUJI XEROX CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0761643-A2 | Cyclobutenedione derivative, manufacturing method thereof and non-linear optical device containing the same | FUJI XEROX CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |