SCHEMBL8096636

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6702831	0.81	NOS1 (0.39)	GABRA1GABRB2AKR1B1ASIC3PDPK1
	SCHEMBL8089097	0.79	ALOX5 (0.48)	GABRA1GABRB2ALOX5ASIC3PDPK1
	SCHEMBL29892631	0.77	GABRA1 (1.00)	GABRA1GABRB2AKR1B1POLBALOX5
	SCHEMBL252293	0.77	GABRA1 (1.00)	GABRA1GABRB2AKR1B1POLBALOX5
	SCHEMBL219308	0.76	NOS1 (0.55)	GABRA1GABRB2ALOX5CNR2NOS3
	SCHEMBL9311059	0.73	GABRA1 (0.92)	GABRA1GABRB2AKR1B1POLBALOX5
	SCHEMBL7072944	0.73	FEN1 (0.37)	GABRA1GABRB2AKR1B1
	SCHEMBL2185735	0.72	GABRA1 (0.82)	GABRA1GABRB2AKR1B1POLBALOX5
	SCHEMBL13978637	0.72	AKR1B1 (0.70)	GABRA1GABRB2AKR1B1POLBALOX5
	SCHEMBL3819967	0.71	GABRA1 (0.68)	GABRA1GABRB2AKR1B1POLBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.