SCHEMBL8097006

SCHEMBL8097006

CC(C)C(c1ccccc1)C(Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.40
TSHR P16473 2/20 0.40
HTT P42858 1/20 0.40
SLC6A4 P31645 1/20 0.39
CYP2D6 P10635 2/20 0.39
ADRA2C P18825 2/20 0.39
CHRM2 P08172 1/20 0.39
ADRA1A P35348 1/20 0.39
RGS12 O14924 1/20 0.39
GLA P06280 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
PKM P14618 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
NFKB1 P19838 1/20 0.39
HTR2A P28223 1/20 0.39
CYP2C19 P33261 1/20 0.39
THPO P40225 1/20 0.39
GNAI1 P63096 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10360017 0.80 RIPK1 (0.45) TAAR1SLC6A4CYP2D6ADRA2CCHRM2
SCHEMBL9688584 0.78 PTGS1 (0.54) TSHRCYP2D6MEN1KMT2A
SCHEMBL9687417 0.77 AOC3 (0.41) SLC6A4CYP2C19MEN1KMT2AAOC3
SCHEMBL16908665 0.77 HTT (0.45) HTTCYP2D6CYP3A4HSD17B10LMNA
SCHEMBL9248072 0.77 ACHE (0.41) TAAR1MEN1KMT2AAOC3ALDH1A1
SCHEMBL8097109 0.76 TAAR1 (0.40) TAAR1SLC6A4CYP2D6ADRA2CCHRM2
SCHEMBL14367700 0.76 TAAR1 (0.40) TAAR1SLC6A4CYP2D6ADRA2CCHRM2
SCHEMBL9686706 0.76 IDO1 (0.39) SLC6A4CYP2D6CYP3A4MEN1KMT2A
SCHEMBL9249693 0.76 UGT2B7 (0.53) TSHRSLC6A4CYP2D6ADRA2CCYP3A4
SCHEMBL9688011 0.76 ADRB1 (0.53) TSHRADRA2CADRA1ACYP3A4NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1053990-A2 A method of producing an aromatic ketone and an aromatic ketone composition containing it TORAY INDUSTRIES, INC. (JP) 2000-11-22 EP disclosed