SCHEMBL8097187

SCHEMBL8097187

CCCC12C=CC(CC1C(=O)OC)C2

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 2/20 0.35
DNTT P04053 2/20 0.32
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9802814 0.83 OPRM1 (0.30)
SCHEMBL9802803 0.80 OPRK1 (0.34)
SCHEMBL565528 0.76
SCHEMBL5395254 0.75 KMT2A (0.30) KMT2A
SCHEMBL7638347 0.75 HPSE (0.33)
SCHEMBL8613888 0.73 SLC6A4 (0.31)
SCHEMBL2465589 0.72 ATM (0.33) POLBATM
SCHEMBL29552402 0.72 ATM (0.33) ATM
SCHEMBL4404945 0.70 CYP2D6 (0.32)
SCHEMBL710693 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103445-A POLYMER OF A T-BUTYL ESTER OF NORBORNENE CARBOXYLIC ACID ANALOG, A PHOTOACID GENERATOR, AND PLASTICIZER COMPRISING A DI-TERT-BUTYL ESTER OF A POLYCYCLIC DICARBOXYLIC ACID; TRANSPARENCY AT 193 NM AND AN ETCH RESISTANCE; RESOLUTION BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2000-08-15 US disclosed