SCHEMBL809747

SCHEMBL809747

NC1CCCCC1NS(=O)(=O)c1cccc(Cl)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PTGES2 Q9H7Z7 7/20 0.46
TSHR P16473 1/20 0.43
PTPN11 Q06124 1/20 0.42
NPY5R Q15761 1/20 0.40
MCOLN3 Q8TDD5 1/20 0.40
PGR P06401 1/20 0.40
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 1/20 0.39
SLC40A1 Q9NP59 1/20 0.39
CCR4 P51679 2/20 0.38
GHSR Q92847 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10453953 0.82 ALDH1A1 (0.77) ALDH1A1L3MBTL1PTGES2TSHRMCOLN3
SCHEMBL4031272 0.79 ALDH1A1 (0.66) ALDH1A1L3MBTL1PTGES2TSHRMCOLN3
SCHEMBL810171 0.77 NPY5R (0.63) ALDH1A1L3MBTL1NPY5RMCOLN3LMNA
SCHEMBL810572 0.76 ALDH1A1 (0.50) ALDH1A1PGRLMNAGAASMN1; SMN2
SCHEMBL810008 0.75 MAPK1 (0.59) ALDH1A1TSHRMCOLN3LMNAGAA
SCHEMBL810835 0.74 ALDH1A1 (0.53) ALDH1A1TSHRMCOLN3LMNAGAA
SCHEMBL14455217 0.74 ALDH1A1 (0.65) ALDH1A1MCOLN3LMNAGAASMN1; SMN2
SCHEMBL5796406 0.74 ALDH1A1 (0.65) ALDH1A1MCOLN3LMNAGAASMN1; SMN2
SCHEMBL6055248 0.74 ALDH1A1 (0.65) ALDH1A1MCOLN3LMNAGAASMN1; SMN2
SCHEMBL810500 0.74 ALDH1A1 (0.38) ALDH1A1L3MBTL1TSHRMCOLN3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2399895-B1 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU (JP) 2018-08-08 EP disclosed
US-8558033-B2 Process for producing optically active aliphatic fluoroalcohol KANTO KAGAKU KABUSHIKI KAISHA (JP) 2013-10-15 US disclosed
US-20110319671-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL KANTO KAGAKU KABUSHIKI KAISHA (JP) 2011-12-29 US disclosed
EP-2399895-A2 Process for producing optically active aliphatic fluoroalcohol Kanto Kagaku Kabushiki Kaisha (JP) 2011-12-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319671-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALIPHATIC FLUOROALCOHOL ADH1A, ADH1C, ADH5 ALDH1A1 5/4885L3MBTL1 3637/4885PTGES2 3252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.