Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978055 | 0.89 | NPR3 (0.44) | SCN9ASMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8096382 | 0.84 | SCN9A (0.42) | ADORA3ADORA2AADORA2BADORA1SCN9A | |
| SCHEMBL8096388 | 0.84 | SCN9A (0.42) | ADORA3ADORA2AADORA2BADORA1SCN9A | |
| SCHEMBL8097547 | 0.83 | SIRT5 (0.43) | SCN9ASMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL7978040 | 0.79 | HTR7 (0.46) | SCN9ASMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL8101266 | 0.79 | HTR7 (0.46) | SCN9ASMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL7978091 | 0.75 | SCN9A (0.44) | SCN9ASMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL7971320 | 0.73 | ADORA3 (0.37) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL7960038 | 0.71 | SCN9A (0.41) | SCN9ASIRT5 | |
| SCHEMBL3433353 | 0.70 | HTR7 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060170-A1 | OPTICALLY ACTIVE SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999044999-A1 | OPTICALLY ACTIVE SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-10 | — | — | WO | disclosed |