Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105978 | 0.89 | TP53 (0.42) | MAPTALDH1A1TP53 | |
| SCHEMBL8097540 | 0.89 | POLB (0.36) | NPC1MAPTALDH1A1ALOX5TP53 | |
| SCHEMBL8103588 | 0.87 | NOTUM (0.40) | CSNK1E | |
| SCHEMBL8098702 | 0.86 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL8102959 | 0.86 | SMN1; SMN2 (0.38) | PKMMAPTALDH1A1 | |
| SCHEMBL8098460 | 0.86 | NTMT1 (0.35) | CSNK1EMAPTALDH1A1TP53 | |
| SCHEMBL8097382 | 0.85 | FAAH (0.32) | ALDH1A1MGLLTP53 | |
| SCHEMBL8099147 | 0.85 | POLB (0.41) | NPC1MAPTALDH1A1TP53 | |
| SCHEMBL8096915 | 0.85 | ALDH1A1 (0.38) | NPC1ALDH1A1MGLLALOX5 | |
| SCHEMBL8098677 | 0.84 | MAPT (0.38) | NPC1CSNK1EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |