Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089448 | 0.87 | LMNA (0.35) | SLC9A1LMNA | |
| SCHEMBL8088976 | 0.85 | LMNA (0.32) | LMNA | |
| SCHEMBL8358558 | 0.79 | LMNA (0.45) | L3MBTL1LMNA | |
| SCHEMBL8358390 | 0.79 | ALDH1A1 (0.38) | L3MBTL1LMNA | |
| SCHEMBL7125185 | 0.71 | TDP1 (0.42) | L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL8983516 | 0.71 | SLC9A1 (0.46) | SLC9A1 | |
| Hydrochloric Acid SCHEMBL8804424 | 0.70 | TDP1 (0.41) | L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL8805378 | 0.69 | LMNA (0.40) | LMNA | |
| Hydrochloric Acid SCHEMBL8803119 | 0.69 | LMNA (0.57) | LMNA | |
| SCHEMBL21884475 | 0.69 | LMNA (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001881-A | Ortho-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-14 | — | — | US | claimed |
| EP-0814077-B1 | Benzoylguanidines, process for their preparation and medicaments containing them | HOECHST AG (DE) | 2000-04-05 | — | — | EP | disclosed |
| US-6001881-A | Ortho-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-12-14 | — | — | US | disclosed |
| EP-0814077-A1 | Benzoylguanidines, process for their preparation and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-29 | — | — | EP | disclosed |