Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983935 | 0.87 | CTSK (0.36) | P2RX3MMP2MMP9ANPEPLTA4H | |
| SCHEMBL6937840 | 0.82 | ADAM17 (0.34) | P2RX3MMP2MMP9ANPEPLTA4H | |
| SCHEMBL6947398 | 0.82 | ADAM17 (0.34) | P2RX3MMP2MMP9ANPEPLTA4H | |
| SCHEMBL6943373 | 0.76 | ADAM17 (0.33) | P2RX3MMP2MMP9ANPEPLTA4H | |
| SCHEMBL6937784 | 0.76 | ADAM17 (0.33) | P2RX3MMP2MMP9ANPEPLTA4H | |
| SCHEMBL6942237 | 0.75 | MMP1 (0.37) | MMP2MMP9 | |
| SCHEMBL6983813 | 0.75 | MEN1 (0.36) | MMP2MMP9ANPEPLTA4HLAP3 | |
| SCHEMBL7955132 | 0.74 | ADAM17 (0.44) | P2RX3MMP2MMP9ANPEPLTA4H | |
| SCHEMBL7835552 | 0.74 | ADAM17 (0.44) | P2RX3MMP2MMP9ANPEPLTA4H | |
| SCHEMBL6943556 | 0.73 | ADAM17 (0.33) | P2RX3MMP2MMP9ANPEPLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999001428-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-14 | — | — | WO | disclosed |