Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 4/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8107597 | 0.93 | PRSS1 (0.50) | PRSS1ALDH1A1HSD17B10KDM4EGAA | |
| Sulfuric Acid SCHEMBL7809563 | 0.88 | PRSS1 (0.44) | PRSS1ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL7809571 | 0.81 | PTGER4 (0.46) | PRSS1ALDH1A1HSD17B10KDM4EGAA | |
| Sulfuric Acid SCHEMBL8113341 | 0.79 | ALDH1A1 (0.52) | PRSS1ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL2927441 | 0.78 | PRSS1 (0.49) | PRSS1ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL6023401 | 0.76 | PRSS1 (0.47) | PRSS1ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL10608893 | 0.76 | PRSS1 (0.50) | PRSS1ALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL15585986 | 0.75 | SMN1; SMN2 (0.46) | PRSS1NQO2HDAC6 | |
| SCHEMBL15545993 | 0.75 | PRSS1 (0.44) | PRSS1ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL8412044 | 0.74 | RAPGEF4 (0.55) | PRSS1ALDH1A1HSD17B10KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6024768-A | HUMAN HAIR COLORING; HAIR CONDITIONERS | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 2000-02-15 | — | — | US | disclosed |
| EP-0970041-A1 | NEW DIAMINOALKANE AND OXIDATION DYEING AGENT | Hans Schwarzkopf GmbH & Co. KG (DE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998001418-A1 | NEW DIAMINOALKANE AND OXIDATION DYEING AGENT | HANS SCHWARZKOPF GMBH & CO.KG (DE) | 1998-01-15 | — | — | WO | disclosed |