SCHEMBL8098435

SCHEMBL8098435

COCCc1c(N)cc(-c2cccn2C)c(N)c1CCOC

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7808831 0.76 ADRA1D (0.31)
SCHEMBL7812217 0.76 ADRA1D (0.31)
SCHEMBL6574556 0.73 HTR7 (0.41) ALDH1A1LMNATDP1
SCHEMBL6574519 0.73 PLA2G7 (0.39) ALDH1A1TDP1
SCHEMBL6571021 0.72 BACE1 (0.34) ALDH1A1LMNA
SCHEMBL8100365 0.72 PCSK9 (0.31)
SCHEMBL6575169 0.72
SCHEMBL6571990 0.71 PRKCZ (0.33) ALDH1A1
SCHEMBL7690514 0.70 SERPINE1 (0.33) ALDH1A1LMNA
SCHEMBL7805904 0.69 PTGER4 (0.35) ALDH1A1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed