Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602899 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TDP1KMT2AL3MBTL1KDM4E | |
| SCHEMBL8603854 | 0.84 | TDP1 (0.43) | ALDH1A1TDP1LMNAMAPTKMT2A | |
| SCHEMBL8091881 | 0.81 | MAPT (0.43) | ALDH1A1TDP1LMNAMAPTKMT2A | |
| SCHEMBL8091901 | 0.80 | LMNA (0.40) | ALDH1A1LMNAMAPTKMT2AMAPK1 | |
| SCHEMBL8090679 | 0.78 | MAPT (0.43) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8092253 | 0.78 | USP10 (0.48) | ALDH1A1LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8091947 | 0.77 | SERPINE1 (0.41) | ALDH1A1LMNAMAPTKMT2AL3MBTL1 | |
| SCHEMBL8606858 | 0.77 | MEN1 (0.39) | ALDH1A1TDP1LMNAMAPTKMT2A | |
| SCHEMBL8083681 | 0.75 | MAPT (0.41) | ALDH1A1TDP1LMNAMAPTKMT2A | |
| SCHEMBL8171359 | 0.75 | SERPINE1 (0.39) | ALDH1A1TDP1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136805-A | Quinoxaline dione derivatives, their production and their use in medicaments | SCNERING AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |