Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15354395 | 0.82 | TNKS2 (0.53) | CYP3A4PLA2G7PTGS2PTGS1CHRM2 | |
| SCHEMBL1300021 | 0.82 | ALDH1A1 (0.61) | CYP3A4ALDH1A1HSD17B10PTGS2PTGS1 | |
| SCHEMBL29962162 | 0.82 | AHR (0.54) | CYP3A4ALDH1A1HSD17B10L3MBTL1DHFR | |
| SCHEMBL396194 | 0.82 | ALDH1A1 (0.52) | CYP3A4PLA2G7ALDH1A1HSD17B10PTGS2 | |
| SCHEMBL331060 | 0.82 | AHR (0.54) | CYP3A4ALDH1A1HSD17B10L3MBTL1DHFR | |
| SCHEMBL3802241 | 0.82 | ALDH1A1 (0.52) | CYP3A4PLA2G7ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL23502859 | 0.81 | ALDH1A1 (0.52) | CYP3A4PLA2G7ALDH1A1HSD17B10PTGS2 | |
| SCHEMBL622451 | 0.79 | PLA2G7 (0.44) | CYP3A4PLA2G7PTGS2PTGS1CHRM2 | |
| SCHEMBL3789866 | 0.79 | ALDH1A1 (0.64) | CYP3A4ALDH1A1HSD17B10L3MBTL1DHFR | |
| SCHEMBL397260 | 0.78 | PTGS2 (0.58) | CYP3A4ALDH1A1HSD17B10PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |