Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103735 | 0.91 | DRD2 (0.39) | DRD2DRD4MEN1KMT2ANOTUM | |
| SCHEMBL8098695 | 0.87 | MAPT (0.41) | ALDH1A1NPC1HTTMEN1KMT2A | |
| SCHEMBL8097519 | 0.85 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2POLBCYP3A4DRD2 | |
| SCHEMBL8090514 | 0.84 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL8097540 | 0.83 | POLB (0.36) | ALDH1A1SMN1; SMN2HDAC8HDAC6BCHE | |
| SCHEMBL8105911 | 0.81 | KMT2A (0.35) | ALDH1A1SMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL8103628 | 0.81 | SLC6A4 (0.37) | ALDH1A1SMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL8098702 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HDAC1HDAC8HDAC6RAB9A | |
| SCHEMBL8103924 | 0.81 | — | — | |
| SCHEMBL8105889 | 0.80 | CACNA1H (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |