Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.46 |
| ▸ | CA1 | P00915 | 14/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101100 | 0.90 | CA2 (0.44) | CA2CA1CA9CA12CA5A | |
| SCHEMBL8100630 | 0.88 | CA2 (0.44) | CA2CA1CA9PTGES2CA12 | |
| SCHEMBL4575696 | 0.81 | PTGS1 (0.56) | CA2CA1CA9CA12 | |
| SCHEMBL8098762 | 0.81 | PTGS1 (0.45) | CA2CA1CA9CA12CA5A | |
| SCHEMBL8107618 | 0.81 | NR3C1 (0.42) | CA2CA1CA9PTGES2CA12 | |
| SCHEMBL8091883 | 0.81 | PTGS1 (0.44) | CA2CA1CA9PTGES2CA12 | |
| SCHEMBL8101110 | 0.80 | CA2 (0.44) | CA2CA1CA9CA12CA5A | |
| SCHEMBL8101193 | 0.79 | CA2 (0.43) | CA2CA1CA9PTGES2CA12 | |
| SCHEMBL8100934 | 0.79 | CA2 (0.44) | CA2CA1CA9CA12CA5A | |
| SCHEMBL8091413 | 0.78 | PTGS2 (0.56) | CA2CA1CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848703-B1 | DERIVATIVES OF BENZOSULPHONAMIDES AS INHIBITORS OF THE ENZYME CYCLO-OXYGENASE II | NYCOMED AUSTRIA GMBH (AT) | 2000-09-27 | — | — | EP | disclosed |
| US-6004948-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | NYCOMED AUSTRIA GMBH (AT) | 1999-12-21 | — | — | US | disclosed |