Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945827 | 0.86 | SIGMAR1 (0.51) | ALDH1A1HRH3HTR2AHTR2CHTR2B | |
| SCHEMBL809603 | 0.74 | ALDH1A1 (0.49) | ALDH1A1GID4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9945826 | 0.74 | SIGMAR1 (0.53) | HRH3SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL9945824 | 0.74 | SIGMAR1 (0.55) | HRH3SLC6A4HTR2AHTR2CHTR2B | |
| SCHEMBL9945825 | 0.72 | SIGMAR1 (0.54) | HRH3SLC6A4CYP2C19HTR2AHTR2C | |
| SCHEMBL9945828 | 0.70 | SIGMAR1 (0.51) | HRH3HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL13444088 | 0.66 | GID4 (0.72) | ALDH1A1GID4 | |
| SCHEMBL7324670 | 0.66 | GID4 (0.72) | ALDH1A1GID4 | |
| SCHEMBL3007732 | 0.65 | IDO1 (0.41) | CYP3A4 | |
| SCHEMBL13458177 | 0.64 | ACHE (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1955992-B1 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORP (JP) | 2011-11-23 | — | — | EP | disclosed |
| EP-1955992-A2 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-13 | — | — | EP | disclosed |