Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809935 | 0.74 | ALDH1A1 (0.43) | ALDH1A1CYP3A4CYP2C9CYP2C19GID4 | |
| SCHEMBL808897 | 0.68 | GID4 (0.55) | ALDH1A1KDM4ECASP1HSD17B10LMNA | |
| SCHEMBL11004808 | 0.67 | OPRM1 (0.49) | ALDH1A1KDM4EHSD17B10DRD2DRD4 | |
| SCHEMBL13187266 | 0.66 | ALDH1A1 (1.00) | ALDH1A1POLBHSD17B10KMT2AMAPT | |
| SCHEMBL10376791 | 0.65 | ALDH1A1 (0.49) | ALDH1A1KDM4EKMT2AMAOANPC1 | |
| SCHEMBL29608349 | 0.65 | POLB (0.48) | ALDH1A1POLBKMT2ACYP2C19NPC1 | |
| SCHEMBL9148331 | 0.64 | KDM1A (0.53) | MAOAGID4HTR2ANPC1TP53 | |
| SCHEMBL9145505 | 0.64 | KDM1A (0.53) | MAOAGID4HTR2ANPC1TP53 | |
| SCHEMBL8542014 | 0.64 | SMN1; SMN2 (0.50) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL30563698 | 0.64 | GID4 (0.52) | GID4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1955992-B1 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORP (JP) | 2011-11-23 | — | — | EP | disclosed |
| US-7728154-B2 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2010-06-01 | — | — | US | disclosed |
| US-20080200697-A1 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-21 | — | — | US | disclosed |
| EP-1955992-A2 | Process for the preparation of 1-aryl-3, 4-dihydro-1h-napthalene-2-one | TOKUYAMA CORPORATION (JP) | 2008-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200697-A1 | Process for the preparation of 1-aryl-3,4-dihydro-1H-naphthalene-2-one | SULT1E1, CYP2S1, SULT1A1 | ALDH1A1 874/4885POLB 1111/4885KDM4E 1954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.