Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097784 | 0.87 | MGLL (0.41) | NOTUMALDH1A1ADRB1AADAT | |
| SCHEMBL8090067 | 0.83 | P2RX7 (0.41) | P2RX7NOTUMALDH1A1DRD2DRD3 | |
| SCHEMBL8099397 | 0.75 | MAPT (0.59) | NOTUMALDH1A1AADATHTR1APHOSPHO1 | |
| SCHEMBL8099175 | 0.74 | MAPT (0.58) | P2RX7NOTUMALDH1A1DRD2DRD3 | |
| SCHEMBL8105245 | 0.73 | ALDH1A1 (0.47) | ALDH1A1DRD2DRD3 | |
| SCHEMBL10732284 | 0.73 | L3MBTL1 (0.39) | P2RX7ALDH1A1AADAT | |
| SCHEMBL8098675 | 0.73 | NOTUM (0.41) | P2RX7NOTUMALDH1A1DRD3AADAT | |
| SCHEMBL8103224 | 0.71 | MEN1 (0.44) | ALDH1A1 | |
| SCHEMBL8103735 | 0.70 | DRD2 (0.39) | NOTUMDRD2DRD3ADRB1HTR1A | |
| SCHEMBL8097654 | 0.70 | ALOX15 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |