Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105987 | 0.85 | NPC1 (0.55) | GRM5KDM5BKDM4EALDH1A1POLB | |
| SCHEMBL1659994 | 0.85 | KDM4E (0.52) | GRM5KDM5BKDM4EALDH1A1GAA | |
| SCHEMBL31365868 | 0.83 | KDM5B (0.50) | GRM5KDM5BKDM4EALDH1A1POLB | |
| SCHEMBL28958139 | 0.83 | KDM5B (0.50) | GRM5KDM5BKDM4EALDH1A1POLB | |
| SCHEMBL8105559 | 0.83 | RAB9A (0.54) | KDM4EALDH1A1POLBGAAHPGD | |
| SCHEMBL8102024 | 0.82 | ALDH1A1 (0.55) | KDM5BKDM4EALDH1A1POLBNPC1 | |
| SCHEMBL7925220 | 0.80 | MEN1 (0.57) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL8102158 | 0.80 | NR1H4 (0.50) | KDM5BKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8099804 | 0.79 | RAB9A (0.49) | GRM5KDM4EALDH1A1GAAHPGD | |
| SCHEMBL1659969 | 0.79 | NPC1 (0.47) | KDM5BKDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071930-A | FOR INHIBITION OF MITOSIS OR TUMOR GROWTH | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-06-06 | — | — | US | disclosed |
| US-5994367-A | PREVENT CELL MITOSIS; ANTICARCINOGENIC AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-11-30 | — | — | US | disclosed |