Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365868 | 1.00 | KDM5B (0.50) | KDM5BKMT2ACDC7PIM1GSK3B | |
| SCHEMBL8092386 | 0.85 | NPC1 (0.55) | KDM5BKMT2ACDC7PIM1GSK3B | |
| SCHEMBL1659994 | 0.85 | KDM4E (0.52) | KDM5BKMT2AMAPTTP53THRB | |
| SCHEMBL8100175 | 0.83 | GRM5 (0.55) | KDM5BKMT2APIM1GSK3BHIPK2 | |
| SCHEMBL8105559 | 0.83 | RAB9A (0.54) | KMT2AMAPTKDM4EADORA3ADORA2A | |
| SCHEMBL7925220 | 0.80 | MEN1 (0.57) | KMT2AMAPTTP53KDM4EADORA3 | |
| SCHEMBL8100231 | 0.80 | GRIN1 (0.49) | KDM5BKMT2ACDC7PIM1GSK3B | |
| SCHEMBL8099804 | 0.79 | RAB9A (0.49) | KMT2AMAPTKDM4EADORA3ADORA2A | |
| SCHEMBL1834856 | 0.78 | ADORA3 (0.47) | KDM5BKMT2ACDC7PIM1GSK3B | |
| SCHEMBL8105987 | 0.77 | NPC1 (0.55) | KDM5BKMT2AMAPTKDM4EADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557948-A | Method for preparing pyrido [1,2-a ] pyrimidin-4-one compound selenized at C3 position | 淄博职业学院 | 2023-01-03 | — | — | CN | claimed |
| CN-115557948-A | Method for preparing pyrido [1,2-a ] pyrimidin-4-one compound selenized at C3 position | 淄博职业学院 | 2023-01-03 | — | — | CN | disclosed |