SCHEMBL810020

SCHEMBL810020

COC(=O)CCCCCOc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
KDM4E B2RXH2 2/20 0.61
LMNA P02545 1/20 0.61
LTA4H P09960 2/20 0.58
RAB9A P51151 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HTT P42858 1/20 0.56
HDAC8 Q9BY41 4/20 0.56
HDAC1 Q13547 4/20 0.56
HDAC2 Q92769 4/20 0.56
HDAC3 O15379 3/20 0.56
HDAC4 P56524 3/20 0.56
HDAC7 Q8WUI4 3/20 0.56
HDAC10 Q969S8 3/20 0.56
HDAC11 Q96DB2 3/20 0.56
HDAC6 Q9UBN7 3/20 0.56
HDAC9 Q9UKV0 3/20 0.56
HDAC5 Q9UQL6 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10685473 0.89 FFAR1 (0.61) NPC1LTA4HRAB9ASMN1; SMN2FFAR1
SCHEMBL10944790 0.88 HDAC1 (0.66) MEN1KMT2ALTA4HRAB9AHDAC8
SCHEMBL839640 0.88 HDAC1 (0.66) MEN1KMT2ALTA4HRAB9AHDAC8
SCHEMBL25270797 0.88 HDAC1 (0.66) MEN1KMT2ALTA4HRAB9AHDAC8
Ethane SCHEMBL5322688 0.86 HDAC1 (0.64) MEN1KMT2ALTA4HRAB9AHDAC8
SCHEMBL6335494 0.86 HDAC1 (0.63) MEN1KMT2ALTA4HRAB9AHDAC8
SCHEMBL4275826 0.86 HDAC1 (0.56) KMT2ALMNALTA4HHTTHDAC8
SCHEMBL15104766 0.86 LTA4H (0.63) NPC1MEN1KMT2AKDM4ELMNA
SCHEMBL1171732 0.86 LTA4H (0.63) NPC1MEN1KMT2AKDM4ELMNA
SCHEMBL7748338 0.86 LTA4H (0.63) NPC1MEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 US disclosed
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 US disclosed
US-8372882-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-02-12 US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 US disclosed
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2011-06-02 US disclosed
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-7902319-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2011-03-08 US disclosed
US-7858077-B2 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC (US) 2010-12-28 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2010-05-06 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-7671168-B2 Unsymmetrical aromatic ether diacids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2010-03-02 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed
US-20070141113-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2007-06-21 US disclosed
US-20060173065-A1 Functionalized phenolic esters and amides and polymers therefrom BEZWADA BIOMEDICAL LLC 2006-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100113592-A1 UNSYMMETRICAL AROMATIC ETHER DIACIDS AND ABSORBABLE POLYMERS THEREFROM DDT, ACMSD, HPD NPC1 3905/4885MEN1 4250/4885KMT2A 2412/4885
US-20060173065-A1 Functionalized phenolic esters and amides and polymers therefrom HAAO, HAO2, HCAR3 NPC1 3222/4885MEN1 4878/4885KMT2A 2066/4885
US-20110130448-A1 FUNCTIONALIZED PHENOLIC ESTERS AND AMIDES AND POLYMERS THEREFROM HAO2, HCAR2, HAAO NPC1 3136/4885MEN1 4874/4885KMT2A 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.