Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 1.00 |
| ▸ | HTR1A | P08908 | 7/20 | 0.69 |
| ▸ | HTR2C | P28335 | 5/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117008 | 0.93 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2CBCHE | |
| SCHEMBL466829 | 0.86 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7759816 | 0.83 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8947974 | 0.79 | SIGMAR1 (0.64) | SIGMAR1HTR2C | |
| SCHEMBL8110473 | 0.79 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8109930 | 0.79 | HTR1A (0.69) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8870940 | 0.78 | SIGMAR1 (0.82) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8870202 | 0.78 | SIGMAR1 (0.64) | SIGMAR1HTR1A | |
| SCHEMBL9449586 | 0.77 | SIGMAR1 (0.69) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7759846 | 0.76 | SIGMAR1 (1.00) | SIGMAR1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673933-B1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR (FR) | 2000-11-08 | — | — | EP | claimed |
| US-5688811-A | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | claimed |
| EP-0673933-A1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | claimed |
| EP-0673933-B1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR (FR) | 2000-11-08 | — | — | EP | disclosed |
| CN-1055924-C | Novel aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 2000-08-30 | — | — | CN | disclosed |
| US-5688820-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |
| US-5688811-A | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |
| US-5534511-A | AFFINITY FOR SIGMA RECEPTORS, ANTIINFLAMMATORY, TREATMENT OF ARTHRITIS | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| CN-1112114-A | Novel aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1995-11-22 | — | — | CN | disclosed |
| EP-0673933-A1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |