Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 2/20 | 0.36 |
| ▸ | ADH1A | P07327 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15247510 | 1.00 | ADH1C (0.36) | ADH1CADH1AKMT2AMEN1KDM4E | |
| SCHEMBL2110093 | 0.92 | GAA (0.32) | ADH1CADH1AKMT2AMEN1KDM4E | |
| SCHEMBL3862705 | 0.86 | — | — | |
| SCHEMBL717182 | 0.75 | GABRA1 (0.50) | — | |
| SCHEMBL11180984 | 0.74 | CA1 (0.33) | CA1CA12CA7CA14LOXL2 | |
| SCHEMBL25249455 | 0.73 | APLNR (0.57) | KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL190753 | 0.73 | GABRA1 (0.48) | — | |
| SCHEMBL12520057 | 0.73 | ALDH1A1 (0.47) | ADH1CADH1AKMT2AMEN1KDM4E | |
| SCHEMBL2743254 | 0.73 | HTR2A (0.40) | KMT2AMEN1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL21422755 | 0.72 | RORC (0.33) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118265691-A | Cyclohexylbeta-hydroxyalkylamines and their medical use | 阿托基公司 | 2024-06-28 | — | — | CN | disclosed |
| EP-3807251-A1 | PHENYL AND PYRIDINYL SUBSTITUTED IMIDAZOLES AS MODULATORS OF RORYT | Janssen Pharmaceutica NV (BE) | 2021-04-21 | — | — | EP | disclosed |
| CN-112334450-A | Phenyl and pyridyl substituted imidazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-02-05 | — | — | CN | disclosed |
| WO-2019244000-A1 | PHENYL AND PYRIDINYL SUBSTITUTED IMIDAZOLES AS MODULATORS OF RORYT | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
| US-6051172-A | PRODUCING AN EXTRUDED MONOFILAMENT PLASTIC LINE, COOLING THE SURFACE OF THE EXTRUDED MONOFILAMENT PLASTIC LINE, SUPPLYING THE SURFACE-COOLED MONOFILAMENT PLASTIC LINE THROUGH AN ELONGATED STRAIGHT GUIDE, CUTTING | Phillips, Robert L. (US) | 2000-04-18 | — | — | US | disclosed |
| US-5941051-A | Package & method of manufacture for flexible cutting line | Phillips, Robert (US) | 1999-08-24 | — | — | US | disclosed |
| US-5871091-A | Package and method of manufacture for flexible cutting line | Phillips, Robert L. (US) | 1999-02-16 | — | — | US | disclosed |
| US-4740538-A | Coated minerals for filling plastics | ENGELHARD CORPORATION (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0255304-A2 | Coated minerals for filling plastics | ENGELHARD CORPORATION (US) | 1988-02-03 | — | — | EP | disclosed |