Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL10703945 | 0.81 | GAA (0.59) | GAACYP2C9CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL8101283 | 0.80 | KDM4E (0.45) | GAACYP2C9CYP1A2CYP2C19KDM4E | |
| SCHEMBL29612322 | 0.79 | MAPT (0.49) | GAACYP2C9CYP1A2CYP2C19KDM4E | |
| SCHEMBL9280351 | 0.78 | ALOX15 (0.49) | GAACYP2C9ALDH1A1MAPTMEN1 | |
| SCHEMBL8100817 | 0.77 | GAA (0.50) | GAACYP2C9KDM4EALDH1A1MAPT | |
| SCHEMBL20631015 | 0.77 | GAA (0.67) | GAACYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL29880960 | 0.77 | GAA (0.50) | GAACYP2C9KDM4EALDH1A1MAPT | |
| SCHEMBL30561156 | 0.77 | ALDH1A1 (0.44) | GAACYP2C9ALDH1A1MAPTMEN1 | |
| SCHEMBL5605404 | 0.77 | ALDH1A1 (0.44) | GAACYP2C9ALDH1A1MAPTMEN1 | |
| SCHEMBL501810 | 0.77 | GAA (0.65) | GAACYP2C9CYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591102-B1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | EP | disclosed |
| US-5488117-A | FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5428162-A | For protecting organic materials against thermal, oxidative or light-induced degradation | CIBA-GEIGY CORPORATION (US) | 1995-06-27 | — | — | US | disclosed |
| US-5369159-A | Heat, oxidation and radiation resistance for polymers | CIBA-GEIGY CORPORATION (US) | 1994-11-29 | — | — | US | disclosed |
| EP-0591102-A1 | 3-(2-Acyloxyethoxyphenyl)benzofuran-2-ones as stabilizers | CIBA-GEIGY AG (CH) | 1994-04-06 | — | — | EP | disclosed |