Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9573819 | 0.85 | GAA (0.45) | ALOX15FFAR1ALDH1A1GAAPPARG | |
| SCHEMBL5605404 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL30561156 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL9319431 | 0.83 | GAA (0.62) | ALOX15FFAR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL29612322 | 0.82 | MAPT (0.49) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL9280347 | 0.81 | PTGDR2 (0.51) | ALOX15ALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL8101288 | 0.78 | GAA (0.49) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL3261989 | 0.78 | LMNA (0.46) | KMT2AMEN1GAALMNA | |
| SCHEMBL501810 | 0.78 | GAA (0.65) | ALDH1A1MAPTKMT2AMEN1GAA | |
| Phosphine SCHEMBL23295992 | 0.76 | GAA (0.63) | ALDH1A1MAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422415-A | Benzofuran derivative, phenolic antioxidant, secondary amine antioxidant; foams | CIBA-GEIGY CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |
| US-5356966-A | Stabilizing organic material against oxidative, thermal or light iinduced degradation | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| US-5356966-A | Stabilizing organic material against oxidative, thermal or light iinduced degradation | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| US-5308899-A | Benzofuranone derivative, phenolic and secondary amine antioxidants | CIBA-GEIGY CORPORATION (US) | 1994-05-03 | — | — | US | disclosed |
| EP-0543778-A1 | Compositions protected against oxydation and scorching, respectively polyetherpolyol and polyurethane | CIBA-GEIGY AG (CH) | 1993-05-26 | — | — | EP | disclosed |