Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | EP300 | Q09472 | 4/20 | 0.33 |
| ▸ | FNTA | P49354 | 5/20 | 0.32 |
| ▸ | FNTB | P49356 | 5/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101919 | 1.00 | CYP19A1 (0.34) | CYP19A1EP300FNTAFNTBCCR5 | |
| SCHEMBL8097065 | 0.89 | CYP19A1 (0.36) | CYP19A1EP300FNTAFNTBCCR5 | |
| SCHEMBL8103769 | 0.89 | CYP19A1 (0.36) | CYP19A1EP300FNTAFNTBCCR5 | |
| SCHEMBL8097062 | 0.89 | CYP19A1 (0.36) | CYP19A1EP300FNTAFNTBCCR5 | |
| SCHEMBL8095919 | 0.87 | ALOX12 (0.40) | CYP19A1CCR5 | |
| SCHEMBL8095949 | 0.87 | FNTA (0.37) | FNTAFNTB | |
| SCHEMBL8095942 | 0.87 | FNTA (0.37) | FNTAFNTB | |
| SCHEMBL8098378 | 0.86 | CYP11B1 (0.34) | CYP19A1FNTAFNTBGPR119 | |
| SCHEMBL8098386 | 0.86 | CYP11B1 (0.34) | CYP19A1FNTAFNTBGPR119 | |
| SCHEMBL8096857 | 0.86 | GPR119 (0.42) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |