SCHEMBL8102014

SCHEMBL8102014

Oc1ccc([Mg]Br)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL15516 0.71
Hydroquinone SCHEMBL460669 0.71 ALOX15 (1.00)
Hydroquinone SCHEMBL11511669 0.71 ALOX15 (1.00)
SCHEMBL23466995 0.69 LMNA (0.50)
SCHEMBL232015 0.69
SCHEMBL137718 0.69
Phloroglucinol SCHEMBL11130971 0.68 ALDH1A1 (0.73)
Hydroquinone SCHEMBL3191616 0.68 ALOX15 (0.73)
SCHEMBL23467126 0.67 NOS3 (0.43)
SCHEMBL5450 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110628302-B Double-component coating based on modified epoxy resin and preparation method thereof 浙江鱼童新材料股份有限公司 2021-08-24 CN disclosed
CN-110628302-A Double-component coating based on modified epoxy resin and preparation method thereof 罗洪财 2019-12-31 CN disclosed
EP-0747354-B1 3-Substituted oxindole derivatives as potassium channel modulators BRISTOL MYERS SQUIBB CO (US) 2000-08-16 EP disclosed
US-5602169-A USEFUL IN REDUCING NEURONAL DAMAGE DURING ISCHEMIC STROKE BRISTOL-MYERS SQUIBB COMPANY (US) 1997-02-11 US disclosed
EP-0747354-A1 3-Substituted oxindole derivatives as potassium channel modulators BRISTOL-MYERS SQUIBB COMPANY (US) 1996-12-11 EP disclosed
US-5565483-A ADMINISTERING AS THERAPY FOR ISCHEMIA, CONVULSIONS OR ASTHMA BRISTOL-MYERS SQUIBB COMPANY (US) 1996-10-15 US disclosed