Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | MITF | O75030 | 4/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092901 | 0.83 | ALDH1A1 (0.45) | LMNAALDH1A1KMT2AHTTMITF | |
| SCHEMBL8102167 | 0.80 | DHODH (0.51) | LMNAALDH1A1KMT2AHTTMITF | |
| SCHEMBL8100744 | 0.80 | MAPT (0.51) | LMNAALDH1A1KMT2AHTTMITF | |
| SCHEMBL8102117 | 0.80 | ALDH1A1 (0.40) | LMNAALDH1A1KMT2AHTTMITF | |
| SCHEMBL8092821 | 0.80 | HSP90AA1 (0.52) | LMNAALDH1A1KMT2AHTTMITF | |
| SCHEMBL8102608 | 0.79 | PTPN1 (0.46) | LMNAALDH1A1KMT2AHTTMITF | |
| SCHEMBL8106476 | 0.79 | FGFR1 (0.46) | LMNAALDH1A1KMT2AHTTMITF | |
| SCHEMBL8100473 | 0.78 | DHODH (0.42) | LMNAALDH1A1KMT2AHTTMITF | |
| SCHEMBL8092964 | 0.78 | MAPT (0.46) | LMNAALDH1A1KMT2AHTTMITF | |
| SCHEMBL8092785 | 0.78 | PTPN1 (0.48) | LMNAALDH1A1HTTMITFL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013674-A | INDENONE AMIDE DERIVATIVES, USEFUL FOR FOR THE INHIBITION OF LEUKOCYTE ADHERENCE TO ENDOTHELIAL CELLS; USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES, AS ARTHRITIS, ASTHAMA, PSORIASIS, RESPIRATORY DISTRESS SYNDROME, STROKE AND ULCER | ELI LILLY AND COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |