⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473210 | 0.67 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL11375741 | 0.66 | CRBN (0.33) | — | |
| SCHEMBL8100963 | 0.64 | CRBN (0.34) | — | |
| SCHEMBL1583554 | 0.62 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL24227250 | 0.61 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL12189561 | 0.61 | CRBN (0.33) | — | |
| SCHEMBL6221243 | 0.61 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL8500707 | 0.58 | — | — | |
| SCHEMBL28864845 | 0.58 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL48327 | 0.58 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087499-A | REACTION OF PERFLUOROALKYLACRYLIC ACID WITH UREA AND ACETIC ANHYDRIDE | F-TECH INCORPORATED (JP) | 2000-07-11 | — | — | US | disclosed |