Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.60 |
| ▸ | HTR1A | P08908 | 6/20 | 0.60 |
| ▸ | HTR2A | P28223 | 5/20 | 0.60 |
| ▸ | DRD4 | P21917 | 4/20 | 0.60 |
| ▸ | HTR7 | P34969 | 4/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.60 |
| ▸ | HRH2 | P25021 | 3/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.60 |
| ▸ | HRH1 | P35367 | 3/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.60 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | DRD1 | P21728 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681457 | 0.86 | HTR1A (0.60) | DRD2HTR1AHTR2ADRD4HTR7 | |
| SCHEMBL7681588 | 0.84 | HTR1A (0.58) | DRD2HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL7690136 | 0.80 | HTR1A (0.66) | HTR1AHTR2ADRD4HTR7ADRA2A | |
| SCHEMBL7684230 | 0.80 | HTR1A (0.52) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL9287993 | 0.76 | DRD4 (0.53) | DRD2HTR1AHTR2ADRD4HTR7 | |
| SCHEMBL4546509 | 0.75 | HTR1A (1.00) | DRD2HTR1AHTR2ADRD4HTR7 | |
| SCHEMBL5372148 | 0.73 | DRD2 (0.66) | DRD2HTR1AHTR2ADRD4HTR7 | |
| SCHEMBL7681514 | 0.73 | — | — | |
| SCHEMBL8595342 | 0.73 | HTR1A (0.74) | DRD2HTR1AHTR2ADRD4HTR7 | |
| SCHEMBL5370401 | 0.73 | HTR1A (0.61) | DRD2HTR1AHTR2ADRD4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057820-A1 | Arylpiperazinylalkyl-3(2H)-pyridazinones as serotonin 5HT and dopamine D2 receptor agonists | FAES, Fabrica Espanola de Productos Quimicos y Farmaceuticos, S.A. (ES) | 2000-12-06 | — | — | EP | claimed |