Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.32 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104036 | 0.91 | MCHR1 (0.38) | MCHR1PSMB5ALDH1A1MAPTLMNA | |
| SCHEMBL8120737 | 0.82 | MAOB (0.35) | — | |
| SCHEMBL8112927 | 0.79 | MCHR1 (0.37) | MCHR1PSMB5ALDH1A1MAPTHTT | |
| SCHEMBL8113921 | 0.78 | RORC (0.46) | MCHR1PSMB5ALDH1A1MAPTLMNA | |
| SCHEMBL8112799 | 0.78 | PSMB5 (0.47) | MCHR1PSMB5ALDH1A1MAPTLMNA | |
| SCHEMBL8113481 | 0.77 | RORC (0.37) | MCHR1PSMB5ALDH1A1MAPTLMNA | |
| SCHEMBL8104607 | 0.77 | RORC (0.36) | ALDH1A1LMNAHTTRORCKMT2A | |
| SCHEMBL8113210 | 0.76 | ALDH1A1 (0.41) | MCHR1PSMB5ALDH1A1MAPTLMNA | |
| SCHEMBL8104603 | 0.76 | MCHR1 (0.46) | MCHR1PSMB5ALDH1A1MAPTLMNA | |
| SCHEMBL8119058 | 0.75 | MCHR1 (0.45) | MCHR1PSMB5ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |