Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104036 | 0.88 | MCHR1 (0.38) | MCHR1ALDH1A1MAPTPANK3TP53 | |
| SCHEMBL8118821 | 0.87 | ALDH1A1 (0.40) | MCHR1ALDH1A1MAPTGAAPOLB | |
| SCHEMBL8113210 | 0.84 | ALDH1A1 (0.41) | MCHR1ALDH1A1MAPTPOLBPANK3 | |
| SCHEMBL8104244 | 0.84 | THRB (0.40) | MCHR1ALDH1A1MAPTPOLBPANK3 | |
| SCHEMBL8112410 | 0.84 | NLRP3 (0.38) | MCHR1ALDH1A1MAPTGAAPOLB | |
| SCHEMBL8113481 | 0.81 | RORC (0.37) | MCHR1ALDH1A1MAPTPANK3TP53 | |
| SCHEMBL8104401 | 0.79 | MCHR1 (0.38) | MCHR1ALDH1A1MAPTPOLBTP53 | |
| Hydrochloric Acid SCHEMBL8118540 | 0.78 | F10 (0.43) | ALDH1A1MAPTPOLBTP53RAB9A | |
| SCHEMBL8113521 | 0.77 | MAPT (0.42) | MCHR1ALDH1A1MAPTPOLBPANK3 | |
| SCHEMBL27538508 | 0.76 | LMNA (0.54) | MCHR1ALDH1A1MAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1268116-A | 3-amidinoaniline derivatives activated blood coagulation factor X inhibitors, and intermediates for producing both | KISSEI PHARMACEUTICAL (JP) | 2000-09-27 | — | — | CN | disclosed |
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |