Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435157 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMHTTALDH1A1MAPT | |
| SCHEMBL8436042 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMHTTALDH1A1MAPT | |
| SCHEMBL8104565 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTALDH1A1MAPT | |
| SCHEMBL8535538 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTALDH1A1MAPT | |
| SCHEMBL8578872 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTALDH1A1MAPT | |
| SCHEMBL9574236 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMHTTALDH1A1MAPT | |
| SCHEMBL8438094 | 0.85 | ALDH1A1 (0.44) | SMN1; SMN2PKMHTTALDH1A1MAPT | |
| SCHEMBL8438096 | 0.85 | ALDH1A1 (0.44) | SMN1; SMN2PKMHTTALDH1A1MAPT | |
| SCHEMBL8104600 | 0.83 | HSD11B1 (0.44) | SMN1; SMN2PKMHTTALDH1A1HSD11B1 | |
| SCHEMBL8110549 | 0.83 | GAA (0.43) | SMN1; SMN2HTTALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |