Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463529 | 0.95 | TSHR (0.42) | CYP3A4MAPTCYP2C9TSHRRAB9A | |
| SCHEMBL8102754 | 0.94 | CTSK (0.42) | CYP3A4MAPTCYP2C9TSHRRAB9A | |
| SCHEMBL8108760 | 0.90 | TSHR (0.44) | CYP3A4MAPTCYP2C9TSHRRAB9A | |
| SCHEMBL27410866 | 0.90 | TSHR (0.44) | CYP3A4MAPTCYP2C9TSHRRAB9A | |
| SCHEMBL8108799 | 0.88 | CCR2 (0.34) | CCR2SIGMAR1CCR5TDP1CTSK | |
| SCHEMBL8439868 | 0.86 | EPHX1 (0.45) | CCR2SIGMAR1TDP1CTSKEPHX1 | |
| SCHEMBL8438723 | 0.86 | EPHX1 (0.45) | CCR2SIGMAR1TDP1CTSKEPHX1 | |
| SCHEMBL8094828 | 0.82 | ALDH1A1 (0.45) | CCR5MAPT | |
| Trifluoroacetic Acid SCHEMBL8104475 | 0.80 | KCNJ1 (0.40) | SIGMAR1CCR5CYP3A4MAPTCYP2C9 | |
| SCHEMBL8440251 | 0.79 | TSHR (0.46) | CYP3A4MAPTCYP2C9TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |