Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7778506 | 0.81 | TSHR (0.50) | MEN1KMT2A | |
| SCHEMBL7794212 | 0.80 | CTSK (0.32) | EPHX2CTSK | |
| SCHEMBL6740235 | 0.80 | FOLH1 (0.44) | EPHX2HDAC1HDAC4HDAC6HDAC8 | |
| SCHEMBL7790037 | 0.79 | CTSK (0.32) | EPHX2HDAC1HDAC4MEN1GAA | |
| SCHEMBL2676200 | 0.78 | EPHX2 (0.43) | EPHX2HDAC1HDAC4HDAC6HDAC8 | |
| SCHEMBL7794209 | 0.78 | HDAC3 (0.33) | EPHX2HDAC1HDAC6HDAC8HDAC2 | |
| SCHEMBL2580673 | 0.78 | CYP1A2 (0.47) | GAAKMT2A | |
| SCHEMBL8104635 | 0.78 | LMNA (0.53) | EPHX2GAAGSTK1 | |
| SCHEMBL6738496 | 0.78 | EPHX2 (0.39) | EPHX2HDAC1HDAC4HDAC6HDAC8 | |
| SCHEMBL134923 | 0.78 | EPHX2 (0.46) | EPHX2HDAC1HDAC6HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117902-A | 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors | GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) | 2000-09-12 | — | — | US | disclosed |
| US-5508275-A | CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-5318987-A | Used for prophylaxis and treats coronary, circulatory and vascular diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-07 | — | — | US | disclosed |