Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.40 |
| ▸ | FNTB | P49356 | 8/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104717 | 0.88 | KCNN4 (0.40) | FNTAFNTBKCNN4KCNA5MAOB | |
| SCHEMBL8113743 | 0.85 | FNTA (0.39) | FNTAFNTBKCNN4KCNA5EP300 | |
| SCHEMBL8120737 | 0.82 | MAOB (0.35) | FNTAFNTBKCNN4KCNA5MAOB | |
| SCHEMBL8113210 | 0.81 | ALDH1A1 (0.41) | EP300 | |
| SCHEMBL3830265 | 0.78 | KCNN4 (0.47) | KCNN4KCNA5MAOBFFAR1FFAR4 | |
| SCHEMBL6982511 | 0.76 | CRHBP (0.52) | KCNN4KCNA5MAOBFFAR1FFAR4 | |
| SCHEMBL8120082 | 0.75 | FFAR1 (0.45) | KCNN4KCNA5MAOBFFAR1FFAR4 | |
| SCHEMBL6982499 | 0.74 | KCNN4 (0.54) | KCNN4KCNA5MAOBFFAR1FFAR4 | |
| SCHEMBL8104391 | 0.74 | MAOB (0.34) | FNTAFNTBKCNN4KCNA5MAOB | |
| SCHEMBL8104607 | 0.71 | RORC (0.36) | FNTAFNTBMAOBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1268116-A | 3-amidinoaniline derivatives activated blood coagulation factor X inhibitors, and intermediates for producing both | KISSEI PHARMACEUTICAL (JP) | 2000-09-27 | — | — | CN | disclosed |
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |