Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104718 | 0.86 | KCNN4 (0.37) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL8113746 | 0.86 | MAOB (0.39) | MAOBFFAR1FFAR4SLC6A2SLC6A4 | |
| SCHEMBL8113212 | 0.83 | MAPT (0.38) | LMNAMAPT | |
| SCHEMBL8120742 | 0.83 | MAOB (0.36) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL6979204 | 0.75 | MAOB (0.46) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL8118826 | 0.72 | MAPT (0.38) | LMNAMAPT | |
| SCHEMBL8104610 | 0.72 | POLB (0.35) | MAOBFFAR1FFAR4 | |
| SCHEMBL8104245 | 0.70 | RORC (0.38) | LMNAMAPT | |
| SCHEMBL8104039 | 0.70 | RAB9A (0.35) | LMNAMAPT | |
| SCHEMBL7057421 | 0.70 | FFAR1 (0.47) | MAOBFFAR1KCNN4KCNA5FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |