Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23422467 | 0.80 | ALDH1A1 (0.40) | MAOBGLA | |
| SCHEMBL7057421 | 0.76 | FFAR1 (0.47) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL8104713 | 0.75 | MAOB (0.40) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL7056650 | 0.74 | KCNN4 (0.45) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL3830265 | 0.74 | KCNN4 (0.47) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL9779957 | 0.74 | FFAR1 (0.50) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL6982499 | 0.72 | KCNN4 (0.54) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL3832721 | 0.71 | FFAR1 (0.45) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL4837137 | 0.71 | MAOB (0.40) | MAOBFFAR1KCNN4KCNA5FFAR4 | |
| SCHEMBL5263127 | 0.71 | GSK3B (0.46) | MAOBFFAR1KCNN4KCNA5MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166694-A1 | Glycinamides | MERCK PATENT GMBH (DE) | 2003-09-04 | — | — | US | disclosed |
| EP-1284961-A1 | GLYCINAMIDES | MERCK PATENT GmbH (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092219-A1 | GLYCINAMIDES | MERCK PATENT GMBH (DE) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166694-A1 | Glycinamides | F11, SERPINC1, F13A1 | MAOB 1287/4885FFAR1 906/4885KCNN4 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.