Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104404 | 0.91 | PSMB5 (0.36) | MCHR1ALDH1A1MAPTHTTMAP2K2 | |
| SCHEMBL8112930 | 0.88 | ALDH1A1 (0.35) | RAB9ANPC1MCHR1ALDH1A1MAPT | |
| SCHEMBL8113212 | 0.86 | MAPT (0.38) | RAB9ANPC1MCHR1ALDH1A1MAPT | |
| SCHEMBL8113483 | 0.86 | NPC1 (0.35) | RAB9ANPC1MCHR1ALDH1A1MAPT | |
| SCHEMBL8120742 | 0.85 | MAOB (0.36) | — | |
| SCHEMBL8118826 | 0.83 | MAPT (0.38) | RAB9ANPC1MCHR1ALDH1A1MAPT | |
| SCHEMBL8104245 | 0.80 | RORC (0.38) | RAB9AALDH1A1MAPTPANK3HTT | |
| SCHEMBL8112413 | 0.80 | NLRP3 (0.36) | RAB9ANPC1MCHR1ALDH1A1MAPT | |
| SCHEMBL8104610 | 0.80 | POLB (0.35) | RORCMEN1KMT2A | |
| SCHEMBL8113521 | 0.77 | MAPT (0.42) | RAB9ANPC1MCHR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |