Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 known ✓ | P47870 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914511 | 0.96 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECLCN2GABRA1 | |
| SCHEMBL6912609 | 0.96 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECLCN2GABRA1 | |
| SCHEMBL6916471 | 0.96 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECLCN2GABRA1 | |
| SCHEMBL6912938 | 0.96 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECLCN2GABRA1 | |
| SCHEMBL8877744 | 0.96 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4ECLCN2GABRA1 | |
| SCHEMBL6915605 | 0.96 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECLCN2GABRA1 | |
| SCHEMBL11182007 | 0.96 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECLCN2GABRA1 | |
| Zinc Ion SCHEMBL6914561 | 0.96 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECLCN2GABRA1 | |
| SCHEMBL11244243 | 0.96 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECLCN2GABRA1 | |
| SCHEMBL6914501 | 0.96 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4ECLCN2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255615-B1 | POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM | SYENSQO SPECIALTY POLYMERS USA LLC (US) | 2026-04-22 | — | — | EP | claimed |
| US-20240017219-A1 | POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2024-01-18 | — | — | US | claimed |
| EP-4255615-A1 | POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM | Solvay Specialty Polymers USA, LLC (US) | 2023-10-11 | — | — | EP | claimed |
| WO-2022122769-A1 | POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2022-06-16 | — | — | WO | claimed |
| US-12630706-B2 | Membrane comprising a blend of polyarylethersulfone and polyaryletherketone and method for manufacturing thereof | SYENSQO SPECIALTY POLYMERS USA, LLC (US) | 2026-05-19 | — | — | US | disclosed |
| EP-4255615-B1 | POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM | SYENSQO SPECIALTY POLYMERS USA LLC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4594552-A1 | MEMBRANE FOR ALKALINE WATER ELECTROLYSIS | Solvay Specialty Polymers USA, LLC (US) | 2025-08-06 | — | — | EP | disclosed |
| EP-4028456-B1 | POROUS ARTICLES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF | SOLVAY SPECIALTY POLYMERS USA (US) | 2024-11-06 | — | — | EP | disclosed |
| WO-2024068332-A1 | MEMBRANE FOR ALKALINE WATER ELECTROLYSIS | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2024-04-04 | — | — | WO | disclosed |
| US-20240017219-A1 | POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2024-01-18 | — | — | US | disclosed |
| EP-4255615-A1 | POLYMER COMPOSITION AND METHOD FOR MANUFACTURING MEMBRANES THEREFROM | Solvay Specialty Polymers USA, LLC (US) | 2023-10-11 | — | — | EP | disclosed |
| US-20220362718-A1 | POROUS ARTICLES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF | SYENSQO SPECIALTY POLYMERS USA, LLC | 2022-11-17 | — | — | US | disclosed |
| US-20190241712-A1 | POROUS ARTICLE COMPRISING A POLYMER AND AN ADDITIVE, PROCESSES FOR THEIR PREPARATION AND USE THEREOF | SOLVAY SPECIALITY POLYMERS USA, LLC | 2019-08-08 | — | — | US | disclosed |
| WO-2018065526-A1 | POROUS ARTICLE COMPRISING A POLYMER AND AN ADDITIVE, PROCESSES FOR THEIR PREPARATION AND USE THEREOF | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2018-04-12 | — | — | WO | disclosed |
| EP-0590885-B1 | Antibiotic carbapenem compounds | ZENECA LTD (GB) | 2000-03-15 | — | — | EP | disclosed |
| US-5571805-A | FOR TREATING BACTERIAL INFECTIONS IN MAMMALS | ZENECA LIMITED (GB) | 1996-11-05 | — | — | US | disclosed |
| US-5527791-A | Carbapenem antibiotic compounds | ZENECA LIMITED (GB) | 1996-06-18 | — | — | US | disclosed |
| EP-0590885-A1 | Antibiotic carbapenem compounds | ZENECA LIMITED (GB) | 1994-04-06 | — | — | EP | disclosed |
| EP-0562855-A1 | Carbapenem compounds as antibiotics | ZENECA LIMITED (GB) | 1993-09-29 | — | — | EP | disclosed |
| US-4490522-A | REACTING POLYHALOGENATED AROMATIC COMPOUND WITH ALKALI METAL SULFIDE IN PRESENCE OF OXYALKYLENE COMPOUND | DAINIPPON INK & CHEMICALS, INC. (JP) | 1984-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630706-B2 | Membrane comprising a blend of polyarylethersulfone and polyaryletherketone and method for manufacturing thereof | LNPK, KCNJ1, ABCB7 | GABRA1 2484/4885GABRB2 2499/4885ALDH1A1 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.