Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30601989 | 0.86 | CHRNB2 (0.55) | LMNACHRNB2CHRNA4ALDH1A1MEN1 | |
| SCHEMBL30023557 | 0.86 | CHRNB2 (0.55) | LMNACHRNB2CHRNA4ALDH1A1MEN1 | |
| SCHEMBL27468480 | 0.86 | CHRNB2 (0.55) | LMNACHRNB2CHRNA4ALDH1A1MEN1 | |
| SCHEMBL7939211 | 0.86 | CHRNB2 (0.55) | LMNACHRNB2CHRNA4ALDH1A1MEN1 | |
| SCHEMBL657597 | 0.86 | CHRNB2 (0.55) | LMNACHRNB2CHRNA4ALDH1A1MEN1 | |
| SCHEMBL10753064 | 0.86 | CHRNB2 (0.58) | LMNACHRNB2CHRNA4ALDH1A1MEN1 | |
| SCHEMBL11454145 | 0.85 | KMT2A (0.63) | LMNAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11586211 | 0.84 | PTGDR2 (0.57) | CHRNB2CHRNA4PTGDR2ALDH1A1MEN1 | |
| SCHEMBL29833128 | 0.84 | MEN1 (0.62) | LMNACHRNB2CHRNA4ALDH1A1MEN1 | |
| SCHEMBL28851332 | 0.84 | MEN1 (0.62) | LMNACHRNB2CHRNA4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| US-8450529-B2 | Branched polyamines and formulations thereof for use in medical devices | COVIDIEN LP (US) | 2013-05-28 | — | — | US | claimed |
| EP-2223952-B1 | Adhesive formulations | TYCO HEALTHCARE (US) | 2012-05-09 | — | — | EP | claimed |
| EP-2172508-B1 | Process for preparing branched polyamines and formulations thereof for use in medical applications | TYCO HEALTHCARE (US) | 2012-03-28 | — | — | EP | claimed |
| EP-2223952-A1 | Adhesive formulations | Tyco Healthcare Group LP (US) | 2010-09-01 | — | — | EP | claimed |
| US-20100209380-A1 | ADHESIVE FORMULATIONS | COVIDIEN LP | 2010-08-19 | — | — | US | claimed |
| US-20100087668-A1 | Branched Polyamines And Formulations Thereof For Use In Medical Devices | TYCO HEALTHCARE GROUP LP | 2010-04-08 | — | — | US | claimed |
| EP-2172508-A1 | Branched polyamines and formulations thereof for use in medical devices | Tyco Healthcare Group LP (US) | 2010-04-07 | — | — | EP | claimed |
| JP-57059855-A | — | — | None | — | — | JP | disclosed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-11351168-B1 | 2,4-disubstituted pyrimidines useful as kinase inhibitors | CELGENE CAR LLC (BM) | 2022-06-07 | — | — | US | disclosed |
| US-10828300-B2 | Substituted 2,4-diaminopyrimidines as kinase inhibitors | CELGENE CAR LLC (BM) | 2020-11-10 | — | — | US | disclosed |
| US-10596172-B2 | 2,4-disubstituted pyrimidines useful as kinase inhibitors | CELGENE CAR LLC (BM) | 2020-03-24 | — | — | US | disclosed |
| EP-3549934-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2019-10-09 | — | — | EP | disclosed |
| US-5382590-A | Gastrointestinal disorders and nervous system disorders | RHONE-POULENC RORER S.A. (FR) | 1995-01-17 | — | — | US | disclosed |
| EP-0590885-A1 | Antibiotic carbapenem compounds | ZENECA LIMITED (GB) | 1994-04-06 | — | — | EP | disclosed |
| JP-S5759855-A | N4-PHENOXYALKANOYLSULFANILAMIDE AND HERBICIDE | SHIONOGI & CO LTD | 1982-04-10 | — | — | JP | disclosed |
| US-4314845-A | N4 -Phenoxyalkanoylsulfanilamides and herbicidal composition containing the same | SHIONOGI & CO., LTD. (JP) | 1982-02-09 | — | — | US | disclosed |
| US-4255511-A | HYDRAZIDO SUBSTITUTED AROMATIC THIOUREAS | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4243739-A | HYDRAZIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100209380-A1 | ADHESIVE FORMULATIONS | NOS2, ICAM1, NOS3 | LMNA 3051/4885CHRNB2 2778/4885CHRNA4 3604/4885 |
| US-11351168-B1 | 2,4-disubstituted pyrimidines useful as kinase inhibitors | DCK, CDK2, DTYMK | LMNA 4283/4885CHRNB2 4603/4885CHRNA4 4695/4885 |
| US-10828300-B2 | Substituted 2,4-diaminopyrimidines as kinase inhibitors | ABL1, DCK, ERBB2 | LMNA 4489/4885CHRNB2 4584/4885CHRNA4 4568/4885 |
| US-20100087668-A1 | Branched Polyamines And Formulations Thereof For Use In Medical Devices | SRM, PNMT, PARG | LMNA 2902/4885CHRNB2 3966/4885CHRNA4 4651/4885 |
| US-10596172-B2 | 2,4-disubstituted pyrimidines useful as kinase inhibitors | DCK, CDK2, DTYMK | LMNA 4283/4885CHRNB2 4603/4885CHRNA4 4695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.